First of all, you can define your default layout (full width, left or right) separately for your pages, your blog page and your single posts via the option panel of Reload.
Notice that you can select your layout for pages and posts independently in page options and in post options.
Single portfolio item has no classic sidebar (there is a specific sidebar area with extra information).
There are 9 predefined Widget Areas included in Reload. Four widget areas in Footer and five more areas for the side.